分子量：Calculated MW: 28kDa/52kDa/58kDa/61kDa/63kDa/64kDa
Observed MW: 63kDa

细胞定位：Cytoplasm, Secreted, cilium basal body, cytoskeleton

稀释方法：WB 1:500 - 1:2000
IF 1:50 - 1:200

总结：This gene encodes a member of a family of secreted and transmembrane proteins. The orthologous gene in mouse functions downstream of smoothened and rab23 to modulate hedgehog signal transduction. This protein is a component of the tectonic-like complex, which forms a barrier between the ciliary axoneme and the basal body. A mutation in this gene was found in a family with Joubert syndrome-13. Alternative splicing results in multiple transcript variants.