SLBP (C-term) Peptide
产品名称： SLBP (C-term) Peptide
英文名称： SLBP (C-term) Peptide
产品编号： P0691
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of SLBP.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human SLBP.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Phosphorylation of stem-loop binding protein (SLBP) on two threonines triggers degradation of SLBP, the sole cell cycle-regulated factor required for regulation of histone mRNA processing, at the end of S phase.
Zheng L, Dominski Z, Yang XC, Elms P, Raska CS, Borchers CH, Marzluff WF.Mol Cell Biol. 2003 Mar;23(5):1590-601.
- 2.
- Stem-loop binding protein, the protein that binds the 3' end of histone mRNA, is cell cycle regulated by both translational and posttranslational mechanisms.
Whitfield ML, Zheng LX, Baldwin A, Ohta T, Hurt MM, Marzluff WF.Mol Cell Biol. 2000 Jun;20(12):4188-98.
- 3.
- The gene for histone RNA hairpin binding protein is located on human chromosome 4 and encodes a novel type of RNA binding protein.
Martin F, Schaller A, Eglite S, Schumperli D, Muller B.EMBO J. 1997 Feb 17;16(4):769-78.
- Entrez GeneID:
- 7884
- Protein Accession#:
- NP_006518;Q14493
- Gene Name:
- SLBP
- Gene Alias:
- HBP
- Gene Description:
- stem-loop binding protein
- Omim ID:
- 602422
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1. [provided by RefSeq
- Other Designations:
- OTTHUMP00000113498,hairpin binding protein, histone,histone binding protein,histone stem-loop binding protein,stem-loop (histone) binding protein