TJP2 Rabbit pAb (APR17485N)
产品名称: TJP2 Rabbit pAb (APR17485N)
英文名称: TJP2 Rabbit pAb (APR17485N)
产品编号: APR17485N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围:
安诺伦(北京)生物科技有限公司
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分子量:Calculated MW: 111-137kDa Observed MW: 160kDa 细胞定位:Cell junction, Cell membrane, Cytoplasmic side, Nucleus, Peripheral membrane protein, adherens junction, tight junction 稀释方法:WB 1:500 - 1:2000 IP 1:50 - 1:200 总结:This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.