PLAU (Human) Chromogenic Activity Assay Kit (Direct Assay)
产品名称: PLAU (Human) Chromogenic Activity Assay Kit (Direct Assay)
英文名称: PLAU (Human) Chromogenic Activity Assay Kit (Direct Assay)
产品编号: KA0976
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- Specification
- Product Description:
- PLAU (Human) Chromogenic Activity Assay Kit (Direct Assay) is developed to determine human PLAU activity in plasma and cell culture supernatants.
- Reactivity:
- Human
- Storage Instruction:
- Store the kit at 4°C.
- Quality Control Testing:
- Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
- Protocol:
- Protocol Download
- MSDS:
- Download
- Regulation Status:
- For research use only (RUO)
- Application Image
- Functional Study
- Entrez GeneID:
- 5328
- Gene Name:
- PLAU
- Gene Alias:
- ATF,UPA,URK,UROKINASE,u-PA
- Gene Description:
- plasminogen activator, urokinase
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000019849,U-plasminogen activator,antagonist of uPA,plasminogen activator, urinary,urokinase plasminogen activator,urokinase-type plasminogen activator amino-terminal fragment
- Gene Pathway
- Related Disease
- Alveolar Bone Loss
- Alzheimer Disease
- Alzheimer disease
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Bacteremia
- Blood Platelet Disorders
- Bronchopulmonary Dysplasia
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- Carcinoma, Transitional Cell
- Cardiovascular Diseases
- Chorioamnionitis
- Chronic Disease
- Cognition
- Colorectal Neoplasms
- Diabetes Complications
- Diabetes Mellitus, Type 1