B Raf (BRAF) Mouse Monoclonal Antibody [Clone ID: LBI1G6]
产品名称: B Raf (BRAF) Mouse Monoclonal Antibody [Clone ID: LBI1G6]
英文名称: B Raf (BRAF) Mouse Monoclonal Antibody [Clone ID: LBI1G6]
产品编号: AMM09114V
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围: WB 1:2000
安诺伦(北京)生物科技有限公司
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别名:B-raf; B-RAF1; BRAF1; NS7; RAFB1 产品概述:Anti-BRAF mouse monoclonal antibody, clone LBI1G6 总结:This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases.This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation,and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma,non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.