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上海信裕生物科技有限公司
DIABLO抗体

DIABLO抗体

商家询价

产品名称： DIABLO抗体

英文名称： DIABLOAntibody

产品编号： XY10434-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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DIABLO抗体

 Applications

In-house applications ELISA, WB, IHC, IP     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
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  • 10434-1-AP;HepG2 cellHepG2 cells were subjected to SDS PAGE followed by western blot with 10434-1-AP(DIABLO antibody) at dilution of 1:1000
  • 10434-1-AP;H-testisImmunohistochemical of paraffin-embedded human testis using 10434-1-AP(DIABLO antibody) at dilution of 1:50 (under 10x lens)
  • 10434-1-AP;H-testisImmunohistochemical of paraffin-embedded human testis using 10434-1-AP(DIABLO antibody) at dilution of 1:50 (under 40x lens)
  • 10434-1-AP;HEK-293 cellsIP Result of anti-DIABLO (IP:10434-1-AP, 4ug; Detection:10434-1-AP 1:500) with HEK-293 cells lysate 2000ug.
Positive WB detected in HepG2 cells, HEK-293 cells, HeLa cells, Jurkat cells, mouse testis tissue, Sp2/0 cells
Positive IP detected in HEK-293 cells
Positive IHC detected in Human testis tissue, human kidney tissue
Recommended dilution WB : 1:500-1:5000
IP : 1:200-1:2000
IHC : 1:20-1:200
DIABLO抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen InformationDIABLO抗体
Immunogen DIABLO fusion protein ag0696 Full name Diablo homolog (Drosophila)
Calculated molecular
weight		 27 kDa Observed molecular 
weight		 20 kDa
GenBank accession 
number		 BC011909 Gene ID (NCBI) 56616
Gene symbol DIABLO Synonyms DIABLO, diablo homolog (Drosophila), Diablo homolog, mitochondrial, DIABLO S, FLJ10537, FLJ25049, SMAC, SMAC3
Background

DIABLO, also named as SMAC, promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. DIABLO inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases. This antibody recognizes all the three isoforms (27 kDa and 22 kDa) of DIABLO. The highest expression was in the testis, adrenal gland, and ears.DIABLO抗体

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