TIMP2 (Human) ELISA Kit
产品名称： TIMP2 (Human) ELISA Kit
英文名称： TIMP2 (Human) ELISA Kit
产品编号： KA0549
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- TIMP2 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human TIMP2.
- Calibration Range:
- 156 to 10000 pg/mL
- Limit of Detection:
- 2 pg/mL
- Reactivity:
- Human
- Storage Instruction:
- Store the kit at 4°C for 4 months. For long term storage, please store at -20°C for 8 months.
- Quality Control Testing:
- Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
- Protocol:
Protocol Download
- MSDS:
- Download
- Suitable Sample:
- Body Fluid, Cell Culture Supernatant, Plasma, Serum, Tissue Lysate
- Sample Volume:
- 100 uL
- Label:
- Biotin-conjugate
- Detection Method:
- Colorimetric
- Regulation Status:
- For research use only (RUO)
- Publication Reference
- 1.
- TIMP-2 mediated inhibition of angiogenesis: an MMP-independent mechanism.
Seo DW, Li H, Guedez L, Wingfield PT, Diaz T, Salloum R, Wei BY, Stetler-Stevenson WG.Cell. 2003 Jul 25;114(2):171-80.
- 2.
- Structure and characterization of the human tissue inhibitor of metalloproteinases-2 gene.
Hammani K, Blakis A, Morsette D, Bowcock AM, Schmutte C, Henriet P, DeClerck YA.J Biol Chem. 1996 Oct 11;271(41):25498-505.
- 3.
- The gene for tissue inhibitor of metalloproteinases-2 is localized on human chromosome arm 17q25.
De Clerck Y, Szpirer C, Aly MS, Cassiman JJ, Eeckhout Y, Rousseau G.Genomics. 1992 Nov;14(3):782-4.
- Application Image
- Quantification
- Entrez GeneID:
- 7077
- Gene Name:
- TIMP2
- Gene Alias:
- CSC-21K
- Gene Description:
- TIMP metallopeptidase inhibitor 2
- Omim ID:
- 188825
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq
- Other Designations:
- tissue inhibitor of metalloproteinase 2,tissue inhibitor of metalloproteinases 2
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Aortic Aneurysm, Abdominal
- Arthritis, Rheumatoid
- Atherosclerosis
- Atrial Fibrillation
- Breast cancer
- Breast Neoplasms
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Carotid Artery Diseases
- Carotid Stenosis
- Cerebral Hemorrhage
- Chorioamnionitis
- Chronic Disease
- Cleft Lip
- Cleft Palate
- Colitis, Ulcerative
- Constriction, Pathologic