重组人蛋氨酸亚砜还原酶A|Human MSRA
产品名称： 重组人蛋氨酸亚砜还原酶A|Human MSRA
英文名称： Recombinant Human Methionine Sulfoxide Reductase A
产品编号： ENZ-621
产品价格： 0
产品产地： 以色列
品牌商标： ProSpec
更新时间： null
使用范围： null
上海高创化学科技有限公司
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- 地址 : 上海市七莘路1890弄11号602
- 邮编 : 201101
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- 邮箱 : gaochem@163.com
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Synonyms
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Mitochondrial peptide methionine sulfoxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase, Protein-methionine-S-oxide reductase, PMSR, MSRA.
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Introduction
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Methionine sulfoxide reductase A (MSRA) is a member of the MsrA Met sulfoxide reductase family. The MSRA enzyme has a vital function as a repair enzyme for proteins which have been inactivated by oxidation. MSRA catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. The three substrates of the MSRA enzyme are peptide-L-methionine, thioredoxin disulfide, and H2O, while its 2 products are peptide-L-methionine (R)-S-oxide and thioredoxin. The MSRA protein is ubiquitous and extremely conserved. Human and animal studies have shown the ultimate levels of expression in kidney and nervous tissue.
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Description
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MSRA Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 237 amino acids (24-235) and having a molecular mass of 26.2kDa.
The MSRA is fused to a 24 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. |
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Source
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Escherichia Coli.
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Physical Appearance
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Sterile Filtered clear colorless solution.
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Formulation
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MSRA protein solution (0.5mg/ml) is supplied in 20mM Tris-HCl buffer, pH8.0, 10% glycerol, 1mM DTT and 50mM NaCl.
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Stability
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Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. |
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Amino acid sequence
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MGSSHHHHHH SSGLVPRGSH MGSHMGNSAS NIVSPQEALP GRKEQTPVAA KHHVNGNRTV EPFPEGTQMA VFGMGCFWGA ERKFWVLKGV YSTQVGFAGG YTSNPTYKEV CSEKTGHAEV VRVVYQPEHM SFEELLKVFW ENHDPTQGMR QGNDHGTQYR SAIYPTSAKQ MEAALSSKEN YQKVLSEHGF GPITTDIREG QTFYYAEDYH QQYLSKNPNG YCGLGGTGVS CPVGIKK.
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Purity
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Greater than 90.0% as determined by SDS-PAGE.
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Usage
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ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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