Melanophilin 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
Melanophilin 抗体

Melanophilin 抗体

商家询价

产品名称： Melanophilin 抗体

英文名称： Melanophilin Antibody

产品编号： XY10338-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 ADCY7抗体

Applications
In-house applications ELISA, WB, IHC, IP, IF     Application not tested? Please see our Guarantee.
Published applications FC, IHC, IP, WB Publications 5 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human
Images
Prev12NextView more validation data
  • 10338-1-AP;A375 cellA375 cells were subjected to SDS PAGE followed by western blot with 10338-1-AP(MLPH antibody) at dilution of 1:1000
  • 10338-1-AP;human skin cancer tissueImmunohistochemical of paraffin-embedded human skin cancer using 10338-1-AP(MLPH antibody) at dilution of 1:50 (under 10x lens)
  • 10338-1-AP;human skin cancer tissueImmunohistochemical of paraffin-embedded human skin cancer using 10338-1-AP(MLPH antibody) at dilution of 1:50 (under 40x lens)
  • 10338-1-AP;HeLa cellsImmunofluorescent analysis of ( -20℃ Ethanol ) fixed HeLa cells using 10338-1-AP( MLPH Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 10338-1-AP;A375 cellsIP Result of anti-MLPH (IP:10338-1-AP, 4ug; Detection:10338-1-AP 1:600) with A375 cells lysate 3600ug.
Positive WB detected in A375 cells
Positive IP detected in A375 cells
Positive IHC detected in Human skin cancer tissue
Positive IF detected in HeLa cells
Recommended dilution WB : 1:200-1:2000
IP : 1:200-1:2000
IHC : 1:20-1:200
IF : 1:20-1:200
 ADCY7抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information ADCY7抗体
Immunogen Melanophilin fusion protein ag0316 Full name Melanophilin
Calculated molecular
weight		 66 kDa Observed molecular 
weight		 66 kDa, 80 kDa
GenBank accession 
number		 BC001653 Gene ID (NCBI) 79083
Gene symbol MLPH Synonyms Exophilin 3, melanophilin, MLPH, SLAC2 A, SLAC2A, Synaptotagmin like protein 2a
Background

Melanophilin (Mlph) is a member of the exophilin subfamily of Rab effector proteins. MLPH is a modular protein, forming a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. It regulates retention of melanosomes at the peripheral actin cytoskeleton of melanocytes, a process essential for normal mammalian pigmentation. Defects in MLPH are a cause of Griscelli syndrome type 3 (GS3), which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. ADCY7抗体

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