CTTN monoclonal antibody, clone 4C6
产品名称： CTTN monoclonal antibody, clone 4C6
英文名称： CTTN monoclonal antibody, clone 4C6
产品编号： MAB10620
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant CTTN.
- Immunogen:
- Recombinant protein corresponding to human CTTN.
- Host:
- Mouse
- Theoretical MW (kDa):
- 80
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In ascites (0.03% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis using CTTN monoclonal antibody, clone 4C6 (Cat # MAB10620) against HeLa (1) , A-431 (2) , MCF-7 (3) , SR-BR-3 (4) , HepG2 (5) and NIH/3T3 (6) cell lysate.
- Entrez GeneID:
- 2017
- Gene Name:
- CTTN
- Gene Alias:
- EMS1,FLJ34459
- Gene Description:
- cortactin
- Omim ID:
- 164765
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Two splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq
- Other Designations:
- 1110020L01Rik,ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate),oncogene EMS1
- Interactome
- Related Disease