分子量：Calculated MW: 85kDa
Observed MW: 76kDa

细胞定位：Cytoplasm, Nucleus

稀释方法：WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:100

总结：The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.