XPC (Human) Recombinant Protein (Q01)
产品名称: XPC (Human) Recombinant Protein (Q01)
英文名称: XPC (Human) Recombinant Protein (Q01)
产品编号: H00007508-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human XPC partial ORF ( NP_004619, 141 a.a. - 250 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- EPVLGDVRESTAFSRSLLPVKPVEIEIETPEQAKTRERSEKIKLEFETYLRRAMKRFNKGVHEDTHKVHLLCLLANGFYRNNICSQPDLHAIGLSIIPARFTRVLPRDVD
- Theoretical MW (kDa):
- 37.84
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 7508
- GeneBank Accession#:
- NM_004628
- Protein Accession#:
- NP_004619
- Gene Name:
- XPC
- Gene Alias:
- XP3,XPCC
- Gene Description:
- xeroderma pigmentosum, complementation group C
- Omim ID:
- 278720
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq
- Other Designations:
- xeroderma pigmentosum group C protein
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Adenoma
- Ataxia telangiectasia
- Azoospermia
- Barrett Esophagus
- Bone Neoplasms
- Brain Neoplasms
- Breast cancer
- Breast Diseases
- Breast Neoplasms
- Carcinoma
- Carcinoma, Basal Cell
- Carcinoma, Hepatocellular
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Renal Cell
- Carcinoma, Squamous Cell
- Carcinoma, Transitional Cell
- Cell Transformation, Neoplastic
- Chromosome Aberrations