HSPD1 monoclonal antibody, clone 2E4
产品名称： HSPD1 monoclonal antibody, clone 2E4
英文名称： HSPD1 monoclonal antibody, clone 2E4
产品编号： MAB1121
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against full length recombinant HSPD1.
- Immunogen:
- Recombinant protein corresponding to full length human HSPD1.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In PBS, pH 7.4 (0.1% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:1000-1:3000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Hsp60 regulation of tumor cell apoptosis.
Ghosh JC, Dohi T, Kang BH, Altieri DC.J Biol Chem. 2008 Feb 22;283(8):5188-94. Epub 2007 Dec 17.
- 2.
- The mitochondrial chaperonin hsp60 is required for its own assembly.
Cheng MY, Hartl FU, Horwich AL.Nature. 1990 Nov 29;348(6300):455-8.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of cell lysates of HeLa (30 ug) were resolved by SDS - PAGE , transferred to NC membrane and probed with HSPD1 monoclonal antibody , clone 2E4 (1 : 1000) (Cat # MAB1121). Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system.
- Entrez GeneID:
- 3329
- GeneBank Accession#:
- NM_002156
- Protein Accession#:
- NP_002147
- Gene Name:
- HSPD1
- Gene Alias:
- CPN60,GROEL,HLD4,HSP60,HSP65,HuCHA60,SPG13
- Gene Description:
- heat shock 60kDa protein 1 (chaperonin)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq
- Other Designations:
- P60 lymphocyte protein,chaperonin,heat shock 60kD protein 1 (chaperonin),heat shock protein 65,mitochondrial heat shock 60kD protein 1 variant 1,mitochondrial matrix protein P1,short heat shock protein 60 Hsp60s1,spastic paraplegia 13 (autosomal dominant)
- Gene Pathway
- Related Disease