ADM polyclonal antibody
产品名称: ADM polyclonal antibody
英文名称: ADM polyclonal antibody
产品编号: PAB4972
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of ADM.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to human ADM.
- Sequence:
- YRQSMNNFQGLRSFGCRFGTCTVQKLAHQIYQFTDKDKDNVAPRSKISPQGY
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In PBS, pH 7.5 (50% glycerol, 0.01% thimerosal)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against synthetic peptide.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Immunoprecipitation
- Enzyme Immunoassay
- Entrez GeneID:
- 133
- Gene Name:
- ADM
- Gene Alias:
- AM
- Gene Description:
- adrenomedullin
- Omim ID:
- 103275
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element. [provided by RefSeq
- Other Designations:
- preproadrenomedullin
- Gene Pathway
- Related Disease
- Bipolar Disorder
- Cardiovascular Diseases
- Cerebral Infarction
- Depressive Disorder, Major
- Diabetes Mellitus, Type 2
- Diabetic Nephropathies
- Edema
- Genetic Predisposition to Disease
- Hypertension
- Hypertension, Renal
- Intracranial Arteriosclerosis
- Kidney Failure
- Kidney Failure, Chronic
- Proteinuria
- Schizophrenia