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上海信裕生物科技有限公司
ROR1抗体

ROR1抗体

商家询价

产品名称: ROR1抗体

英文名称: ROR1Antibody

产品编号: XY20629-1-

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 ROR1抗体Applications

In-house applications ELISA, WB, IHC     Application not tested? Please see our Guarantee.
Published applications IHC Publications 1 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species HUMAN
Images
Prev1NextView more validation data
  • 20629-1-AP;K-562 cellK-562 cells were subjected to SDS PAGE followed by western blot with 20629-1-AP(ROR1 antibody) at dilution of 1:500
  • 20629-1-AP;human breast cancer tissueImmunohistochemistry of paraffin-embedded human breast cancer tissue slide using 20629-1-AP( ROR1 Antibody) at dilution of 1:50 (under 10x lens)
  • 20629-1-AP;human breast cancer tissueImmunohistochemistry of paraffin-embedded human breast cancer tissue slide using 20629-1-AP( ROR1 Antibody) at dilution of 1:50 (under 40x lens)
Positive WB detected in K-562 cells, HeLa cells
Positive IHC detected in Human breast cancer tissue, human ovary tumor tissue
Recommended dilution WB : 1:500-1:5000
IHC : 1:20-1:200
 ROR1抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen ROR1 fusion protein ag14586 Full name Receptor tyrosine kinase-like orphan receptor 1
Calculated molecular
weight
937aa,104 kDa Observed molecular 
weight
130-140 kDa
GenBank accession 
number
BC006374 Gene ID (NCBI) 4919
Gene symbol ROR1 Synonyms DJ537F10.1, NTRKR1, ROR1
Background ROR1抗体

ROR1 is a member of the RTK family of orphan receptors related to muscle specific kinase and Trk neurotrophin receptors (PMID: 18546292). ROR1 is primarily expressed by neural crest cells during embryogenesis. High expression of ROR1 is reported in many types of malignancies and is thought to be involved in tumor growth, apoptosis, and epithelial-mesenchymal transition (PMID: 26245996). The human ROR1 gene encodes a 937-amino acid protein with an Ig-like domain, a cysteine-rich domain, a kringle domain, a tyrosine kinase domain and a proline-rich domain. The calculated molecular weight of ROR1 is 104 kDa, but ROR1 has multiple N-glycosylation sites that generate post-translationally modified ROR1 at 130 kDa (PMID: 24752542). ROR1抗体

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