分子量：Calculated MW: 24kDa
Observed MW: 24kDa

细胞定位：Cytoplasm, Cytoplasmic granule membrane, Cytoplasmic side, Peripheral membrane protein

稀释方法：WB 1:500 - 1:2000
IF 1:50 - 1:100

总结：This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.